Sepiatec GmbH develops separation systems based on HPLC (High Performance Liquid Chromatography) and SFC (Supercritical Fluid Chromatography) technology, enabling our customers to speed up their separation and method development significantly.
Sepmatix 8x Screening HPLC system
The Sepmatix 8x Screening HPLC system is working with eight channels in parallel. The system only uses one external HPLC pump. The flow is separated by the patented Sepmatix Flow Control into eight channels, and the flow in each channel is precisely measured and regulated throughout the entire run. Together with an autosampler and an 8x parallel working detector, the result is an unbelievable compact HPLC system which will instantly enhance the throughput of every research and development laboratory eight times over.
It is not necessary to spend time adapting methods to the new system or to purchase any new costly HPLC columns.
The users can continue to use all the methods and separation material that they were using with their conventional HPLC systems.
The Sepmatix 8x Screening system can separate substances on eight different separation columns simultaneously. This significantly increases sample throughput.
The system consists of three modules: an 8x Flow Control low viscosity version with flow rates of between 0.25 to 1.25 ml/min; an autosampler with syringe pump which injects samples from standard microtiter plates or deep-well microtiter plates onto eight columns (also suitable for vial racks); and an 8x Diode Array Detector with eight analytical flow cells applicable for the spectral range of 200 to 600 nanometers.
The required space for the Sepmatix system is only 55 x 55 x 90 centimeters (W x D X H).
The Sepmatix 8x Flow Control is available as an analytical version (with flow rates from 0.25 to 1.5 m / min per channel), a semiprep version (1.5 to 6.0 ml / min per channel) and a prep version (6.0 to 20 ml / min per channel).
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System |
8 channel HPLC system with Flow Control unit |
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Operating mode |
Up to 8 columns in parallel |
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Number of solvents |
Up to 24 with optional Eluent Rack |
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Pump |
10 ml pump head, incl. low pressure gradient module |
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Operating pressure |
Up to 400 bar |
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Flow Control |
Active flow regulation in 8 channels, |
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Autosampler |
Screening version, parallel injection of |
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Columns |
Up to 250 mm length, any vendor |
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Column Oven |
(Optional) 8 columns, ambient temperature to 70°C |
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Detector |
8x Diode Array Detector, parallel |
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Software |
Sepmatix Control Software, Screening Wizard Software |
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Dimensions |
55 x 55 x 90 cm (W x D x H) |
Sepmatix 8x Screening SFC system
The Sepmatix 8x Screening SFC system combines Sepiatec’s proven parallel HPLC technology with the advantages of supercritical fluid chromatography.
Eight separating columns
The result is the first SFC system with eight separating columns working in parallel, high operating speed and as yet unmatched performance.
In a space of only a few minutes for example enantiomers can be separated on eight different chiral columns at the same time. The automatic variation of the eluents makes it possible to determine the optimal chiral separation in a significantly shorter time than was previously possible.
Best peak resolution
The superb Screening Wizard Software clearly displays the separations achieved in up to 80 chromatograms at the same time. The separation with the best peak resolution is immediately discernible. The software considerably reduces the amount of time the user needs for the selection process. The overview display is extremely suitable for presentations.
As far as the Sepmatix 8x SFC systems technical features are concerned, only one CO2 pump and one modifier pump are needed. Using Sepiatec’s patented Flow Control the flow is divided into eight channels and regulated exactly by electronically controlled valves.
High Standard Equipment
A back pressure regulator, an autosampler, an eight channel diode array detector and a column oven for heating and cooling purposes are part of the standard equipment.
With minor modifications the Sepmatix 8x SFC system is also suited to chromatography using organic solvents.
|
System |
8 channel SFC system with Flow Control unit |
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Operating mode |
Up to 8 columns in parallel |
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Number of solvents |
Up to 18 solvents with optional Sepmatix Eluent Rack |
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CO2 pump |
100 ml pump head, 400 bar |
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Modifier pump |
100 ml pump head, 400 bar |
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Operating pressure |
Up to 300 bar, adjustable online back pressure control |
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Flow Control |
8x Sepmatix Flow Control, 3 – 6 ml / supercritical fluid per channel |
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Injections |
Total loop |
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Columns |
Up to 250 mm length, any vendor |
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Column Oven |
(Optional) 8 columns, ambient temperature to 70° C |
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Detector |
8x Diode Array Detector, 8x 10 mm flow |
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Software |
Sepmatix Control Software, Screening Wizard Software |
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Dimensions |
70 x 55 x 95 cm (W x D x H) |
